Modifying Enzymes
Enzyme Research Laboratories Inc Human a-Thrombin (Factor IIa),1000 U
Please use this part # if ordering a quantity of 10 or more. If less than qty 1-9 please use Fisher part # NC9872266.
Human a-Thrombin (Factor IIa),1000 U,Buffer Composition = 50 mM Sodium Citrate,0.2 M NaCl,0.1% PEG-8000,pH 6.5,Extinction Coefficient (1%) = 18.3,Molecular Weight = 37,000 daltons,Prepared from human Prothrombin by activation with Factor Xa
Supply Solutions Roche - Neuraminidase(Sialidase); from Arthrobacter ureafaciens; pkg of 1 U (100 ul)
Roche - Neuraminidase(Sialidase); from Arthrobacter ureafaciens; pkg of 1 U (100 ul)
ABclonal Technology Acetyl-CoA Carboxylase
Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA the rate-limiting step in fatty acid synthesis There are two ACC forms alpha and beta encoded by two different genes ACC-alpha is highly enriched in lipogenic tissues The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA Multiple alternatively spliced transcript variants divergent in the 5 sequence and encoding distinct isoforms have been found for this gene
New England Biolabs, Inc. EnGen Sau Cas9 – 400 pmol
EnGen Sau Cas9 from Staphylococcus aureus is an RNA-guided DNA endonuclease that catalyzes site-specific cleavage of double-stranded DNA. Targeting requires a ~100 nucleotide guide RNA (gRNA) complementary to the target site, as well as a 5' NNGRRT 3 (N = any, R = A or G) protospacer adjacent motif (PAM) on the DNA strand opposite the target sequence. DNA cleavage by EnGen Sau Cas9 occurs ~3 bases 5' of the PAM. EnGen Sau Cas9 has Simian virus 40 (SV40) T antigen nuclear localization signals (NLS) at both the N- and C-termini of the protein. Schematic representation of Sau Cas9 nuclease sequence recognition and DNA cleavage
Worthington Biochemical Corporation PROTEASE S AUREUS STRAIN V8
Protease, S. Aureus (Endoproteinase Glu-C), 5mg, Code: STAP, Form: Lyophilized powder, Storage Temperature: 2degree to 8degreeC, Source: S. aureus V8, Minimum Activity: > = 500U/mg dry weight, Stability: 12 months
Supply Solutions Roche - DNase I recombinant, RNase-free solution; from bovine pancreas, expressed in Pichia pastoris; pkg of 10,000 U; Hazardous: Y
Roche - DNase I recombinant, RNase-free solution; from bovine pancreas, expressed in Pichia pastoris; pkg of 10,000 U; Hazardous: Y
Supply Solutions Roche - Proteinase K,Recomb.,Pcr Grd.Lyo.,100 Mg
Roche - Proteinase K,recomb.,PCR Grd.lyo.,100 mg; Lyophilized from Pichia pastoris; pkg of 100 mg (03115879001) pkg of 25 mg (03115836001) pkg of 2 x 250 mg (03115801001) pkg of 4 x 250 mg (0311582001)
New England Biolabs, Inc. Tte-UvrD Helicase – 0.5 µg
Tte UvrD Helicase is a repair helicase capable of unwinding double-stranded DNA, without a requirement for a specific flap or overhang structure, from the thermophilic organism Thermoanaerobacter tengcongensis. It is active on a wide range of DNA substrates and, along with its thermostability (active to 70C), Tte UvrD Helicase has been demonstrated to be a useful additive for improving specificity of isothermal amplification reactions, particularly in conjunction with the WarmStart LAMP Kit.
New England Biolabs, Inc. yDcpS – 4000 units
yDcpS is the scavenging decapping enzyme from S. cerevisiae that hydrolyzes the phosphodiester bond between the gamma and beta phosphates of m7G-capped mRNA, producing diphosphorylated 5 ends and m7GMP. yDcpS is capable of decapping mRNAs of various lengths, decaps Cap0 and Cap1 with equal efficiency, and the diphosphorylated 5 end it produces is suitable for recapping with Vaccinia Capping Enzyme.
Abcam Bano x antrone dihydrochloride (AQ4N), Topoisomerase II inhibitor, 50MG
MW 517.4 Da, Purity >97%. Bioreductive AQ4 precursor. Topoisomerase II inhibitor. Converts under hypoxia to DNA-affinic mitoxantrone (ab141041) structural analog. Induces DNA intercalation. Shows antitumor effects in vivo. .
The product is subject to the following: Abcam Restricted Use Statement
ABclonal Technology GABA transaminase (ABAT) Rabbit mAb
4-aminobutyrate aminotransferase (ABAT) is responsible for catabolism of gamma-aminobutyric acid (GABA), an important, mostly inhibitory neurotransmitter in the central nervous system, into succinic semialdehyde. The active enzyme is a homodimer of 50-kD subunits complexed to pyridoxal-5-phosphate. The protein sequence is over 95% similar to the pig protein. GABA is estimated to be present in nearly one-third of human synapses. ABAT in liver and brain is controlled by 2 codominant alleles with a frequency in a Caucasian population of 0.56 and 0.44. The ABAT deficiency phenotype includes psychomotor retardation, hypotonia, hyperreflexia, lethargy, refractory seizures, and EEG abnormalities. Multiple alternatively spliced transcript variants encoding the same protein isoform have been found for this gene.